Here are the 55 US AI startups that raised $100M or more in 2025 | TechCrunch

The AI industry entered 2025 with strong momentum.

There were49 startups that raised funding rounds worth $100 millionor more in 2024, per our count at TechCrunch; three companies raised more than one “mega-round,” and seven companies raised rounds that were $1billionin size or larger.

The industrydidn’tslow down in2025.Whilelesscompanies raised rounds larger than $1 billion,four—Anthropic raised two roundsover$1 billion— significantly more companies raisedmultiple roundscompared to 2024, eight.

How will 2026 compare? Elon Musk’sxAIannounced a$20 billionSeries Eroundand Sam Altman’s braincomputer interfacestartup Merge Labs raised a$250 million seed round(with OpenAI as the lead investor) inthefirst few weeks of 2026,so signspoint to another strong year.Of course,it’sstillearly;we’llbe watching to see if the momentum continues.

Here are all the U.S. AI companies that raised $100 million last year:

December:

• Austin, Texas-basedMythic, which builds power-efficientcomputefor AI, raised a$125 million venture roundthat was led by DCVC. The round was announced on December 17 and included SoftBank, NEA and Linse Capital, among other investors.

• Chai Discoveryannounced a$130 million Series B roundon December 15. The round valued the company thatbuilds AI models for biotech and drug discovery at$1.2 billion. Oak HC/FT and General Catalyst co-led the round.

• Generative media platformFalannounced its third funding round of 2025 on December 9. This$140 million Series D roundwas led by Sequoia and valued the company at more than$4.5 billion.

• Unconventional AIannounced a monster$475 million seed roundled by Lightspeed Venture Partners and Andreesen Horowitzon December 8. The round valued the one-year-old startup, which is rethinking the foundation of computers in the age of AI, atnearly$4.5billion.

• Boston-based7AI,which builds cybersecurity AI agents,raised a $130 million Series A roundthat was announced on December 4. Index Ventures led the round with participation from Greylock, Spark Capital and CRV, among others.

November

• All-in-one AI workspace platformGensparkannounced a$275 million Series B roundthat valued the company at $1.25billionon November 20.The roundincluded Emergence Capital Partners, SBI Investment, and LG Technology Ventures, among others.

• Luma AI, which builds models used for photo and video creation, raised$900 million in a Series C roundthat valued the startup at$4billion. The round was led byHumainwith participation from Andreessen Horowitz, AMDVenturesand Amplify Partners, among others.

• Anysphere, the maker of viral vibe-coding platform Cursor, raised$2.3 billionin afundingroundthat valued the company at$29.3 billion. The round was announced on November 13 and is the company’s second funding round this year.

• Parallel, which builds web infrastructure for AI agents, raised a$100 million Series A roundthat was announced on November 12. The round wasco-led by Index Ventures and Kleiner Perkins.

• Healthcare AI agent startupHippocratic AIraised a$126million Series C roundthat valued the company at$3.5 billion. The round wasthe company’s second this year, wasannounced on November 3, and was led by Avenir Growth.

October

• Fireworks AI, a platform that allows users to build AI applications usingopen sourcemodels, raised a$250 million Series C roundthat was announced on October 28. The roundvalued the company at$4 billion.

• Enterprise AI startupUniphoreis valued at$2.5 billionafter a$260 million Series F roundthat wasannouncedonOctober 22. The roundincludedSnowflake Ventures, Nvidia, Databricks Ventures,and AMD,among others.

• Sesame, a voice AI company, raised a$250 million Series B roundco-led by Sequoia and Spark Capital. The round was announced on October 21and alsoincludedSignalRankas a participant.

• Cambridge,Massachusetts’sbasedOpenEvidence, which buildsan AI chatbotfor the medical field, raised its second funding round of 2025. The$200 million SeriesC roundwas announced on October 20andvaluedthe company at$6 billion.

• Lila Sciences, which is looking to build a science superintelligence platform, announced its second funding round of 2025 on October 14.The$350 million Series A roundwas co-led byBraidwelland Collective Global.

• DeepSeek competitorReflectionAIannounced its secondmega-roundof the year onOctober 9. The$2 billionSeries B roundvalued the company at$8 billionand was led by Nvidia.

• EvenUp,which builds AI for the personal injury legal field, announced a$150 million Series E roundthat valued the company atmore$2 billionon October 7. The round was led by Bessemerwith participation fromLightspeed, Bain Capital andSignalFire, among others.

September

• Periodic Labs,which is building an AI scientist, announced a$300 million seed roundon September 30. Felicis and Andreessen Horowitz led the round with participation from Nvidia, Lightspeed, and Khosla Ventures, among others.

• CerebrasSystems, an AI infrastructure company,raised a sizable$1.1 billionSeries G roundthat valued the company at$8.1 billion. The round was announced on September 30 and was co-led by Fidelity and AtreidesManagement.

• Modularannounced a$250 millionfundingroundon September 24.The round was led byUSInnovative Technology Fundwith participation from GV, Greylock, and General Catalyst, among others.

• DistylAI,which builds AI enterprise software,raised a$175 million Series B roundthat was announced on September 23. This round valued the startup at$1.8billionandincluded investors likeKhosla Ventures and Lightspeed.

• AI infrastructure startupUpscale AIraised a sizable$100 million seed roundthat was co-led by MaverickSilicon and Mayfield. The round was announced on September 17 and also includedStepStoneGroup, Stanford University,and Qualcomm Ventures, among others.

• Groq, an AI inference company, raised a$750 million Series D-3 roundthat valued the company atnearly$6.9billion. The round was announced on September 17 and was led byDisruptive.

• AI training startupInvisible Technologieswas valued at$2 billionafter a$100 million fundraisethat was announced on September 16. Theraisewas ledby Vanara Capital with participation fromGreycroft,TallwoodsCapital, and Freestyle Capital, among others.

• Cognition AI, the creator of vibe-coding agent Devin, raised a$400 million Series C roundthat was announced on September 8. The round was led byFoundersFund and valued the company at$10.2 billion.

• AI Infrastructure startupBasetenraised a$150 million Series D roundthat valued the company at$2.1 billion. TheSeptember 5round was led by Bond with participation fromCapitalG, IVP andSpark Capital, among others.

• Bret Taylor’s customer service AI agent platformSierraraised $350 millionin a round led byGreenoaksCapital. This fundraise wasannouncedon September 4 and valued Sierra at more than$10billion.

• You.com, apersonalized AI search engine,raised a$100 million Series C roundled by Cox Enterprises. The round was announced on September 3 and valued the company at$1.5 billion.

• AI research lab Anthropic raised its second round of 2025 inSeptember.Anthropicannounced a$13 billionSeries F roundon September 2 that valued the company at$183 billion. The round wasledbyIconiq,Fidelity,and Lightspeed.

August

• Healthcare and housing automation platform EliseAI raised $250 million in a Series E round that valued the startup at $2.2 billion. The round, which was announced on August 20, was led by Andreessen Horowitz.
• Decart, an AI research lab, raised $100 million at a $3.1 billion valuation. The round included Sequoia Capital, Benchmark, and Zeev Ventures, among others, and was announced on August 7.

July

• Generative media platform Fal raised a $125 million Series C round led by Meritech Capital Partners. The company announced the round, which values Fal at $1.5 billion, on July 31. Salesforce Ventures, Shopify Ventures, Google AI Futures Fund, and others joined the round.
• Five-year-old Ambience Healthcare, which is building an AI healthcare operating system, raised a $243 million Series C round that was led by Oak HC/FT and Andreessen Horowitz. Kleiner Perkins, OpenAI Startup Fund, Smash Capital, and others also participated in the round.
• Reka AI, an AI research lab, raised $110 million in a round that included Snowflake and Nvidia. The Series B round was announced on July 22 and values the company at $1 billion.
• AI research lab Thinking Machines Lab confirmed that it raised $2 billion on July 15. This sizable seed round was led by Andreessen Horowitz with participation from Nvidia, Accel, and AMD, among others. The round values the company at $12 billion.
• Cambridge, Massachusetts-based OpenEvidence, which is building an AI-powered search tool for clinicians, raised $210 million at a $3.5 billion valuation. The Series B round was announced on July 15 and was led by Kleiner Perkins and GV.
• Harmonic, which is building a mathematical reasoning engine, raised a $100 million Series B round led by Kleiner Perkins. The round was announced on July 10 and values the company at $875 million.

June

• Healthcare AI unicorn Abridge announced it raised a $300 million Series E round that values the company at $5.3 billion. The round was led by Andreessen Horowitz with Khosla Ventures participating. It was the company’s second round of 2025.
• Harvey, which builds AI tools for the legal industry, announced it raised its second $300 million round of 2025 on June 23. This latest Series E round was co-led by Kleiner Perkins and Coatue and brings the company’s valuation to $5 billion.
• Healthcare AI startup Tennr announced it raised a $101 million Series C round led by IVP with participation from Lightspeed Venture Partners, GV, and Andreessen Horowitz, among others. The round values the company at $605 million.
• Enterprise search startup Glean continues to rake in cash. The company announced a $150 million Series F round on June 10, led by Wellington Management with participation from Sequoia, Lightspeed Venture Partners, and Kleiner Perkins, among others. Glean is now valued at $7.25 billion.
• Anysphere, the AI research lab behind AI coding tool Cursor, raised a sizable $900 million Series C round that values the company at nearly $10 billion. The round was led by Thrive Capital with participation from Andreessen Horowitz, Accel, and DST Global.

May

• AI data labeling startup Snorkel AI announced a $100 million Series D round on May 29, valuing the company at $1.3 billion. The round was led by Addition with participation from Prosperity7 Ventures, Lightspeed Venture Partners, and Greylock.
• LMArena, a popular, community-driven benchmarking tool for AI models, raised a $100 million seed round that valued the startup at $600 million. The round was announced on May 21 and was co-led by Andreessen Horowitz and UC Investments. Lightspeed Venture Partners, Kleiner Perkins, and Felicis also participated, among others.
• Las Vegas-based AI infrastructure company TensorWave announced a $100 million Series A round on May 14. The round was co-led by Magnetar Capital and AMD Ventures with participation from Prosperity7 Ventures, Nexus Venture Partners, and Maverick Silicon.

April

• SandboxAQ closed a $450 million Series E round on April 4 that valued the AI model company at $5.7 billion. The round included Nvidia, Google, and Bridgewater Associates founder Ray Dalio among other investors.
• Runway, which creates AI models for media production, raised a $308 million Series D round that was announced on April 3, valuing the company at $3 billion. It was led by General Atlantic. SoftBank, Nvidia, and Fidelity also participated.

March

• AI behemoth OpenAI raised a record-breaking $40 billion funding round that valued the startup at $300 billion. This round, which closed on March 31, was led by SoftBank with participation from Thrive Capital, Microsoft, and Coatue, among others.
• On March 25, Nexthop AI, an AI infrastructure company, announced that it had raised a Series A round led by Lightspeed Venture Partners. The $110 million round also included Kleiner Perkins, Battery Ventures, and Emergent Ventures, among others.
• Cambridge Massachusetts-based Insilico Medicine raised $110 million for its generative AI-powered drug discovery platform as announced on March 13. This Series E round valued the company at $1 billion and was co-led by Value Partners and Pudong Chuangtou.
• AI infrastructure company Celestial AI raised a $250 million Series C round that valued the company at $2.5 billion. The March 11 round was led by Fidelity with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
• Lila Sciences raised a $200 million seed round as it looks to create a science superintelligence platform. The round was led by Flagship Pioneering. The Cambridge, Massachusetts-based company also received funding from March Capital, General Catalyst, and ARK Venture Fund, among others.
• Brooklyn-based Reflection.Ai, which looks to build superintelligent autonomous systems, raised a $130 million Series A round that values the 1-year-old company at $580 million. The round was led by Lightspeed Venture Partners and CRV.
• AI coding startup Turing closed a Series E round on March 7 that valued the startup, which partners with LLM companies, at $2.2 billion. The $111 million round was led by Khazanah Nasional with participation from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
• Shield AI, an AI defense tech startup, raised $240 million in a Series F round that closed on March 6. This round was co-led by L3Harris Technologies and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Innovative Technology Fund, among others. The round valued the company at $5.3 billion
• AI research and large language model company Anthropic raised $3.5 billion in a Series E round that valued the startup at $61.5 billion. The round was announced on March 3 and was led by Lightspeed with participation from Salesforce Ventures, Menlo Ventures, and General Catalyst, among others.

February

• Together AI, which creates open source generative AI and AI model development infrastructure, raised a $305 million Series B round that valued the company at $3.3 billion. The February 20 round was co-led by Prosperity7 and General Catalyst with participation from Salesforce Ventures, Nvidia, Lux Capital, and others.
• AI infrastructure company Lambda raised a $480 million Series D round that was announced on February 19. The round valued the startup at nearly $2.5 billion and was co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Invest, and others also participated.
• Abridge, an AI platform that transcribes patient-clinician conversations, was valued at $2.75 billion in a Series D round that was announced on February 17. The $250 million round was co-led by IVP and Elad Gil. Lightspeed, Redpoint, and Spark Capital also participated, among others.
• Eudia, an AI legal tech company, raised $105 million in a Series A round led by General Catalyst. Floodgate, Defy Ventures, and Everywhere Ventures also participated in the round in addition to other VC firms and numerous angel investors. The round closed on February 13.
• AI hardware startup EnCharge AI raised a $100 million Series B round that also closed on February 13. The round was led by Tiger Global with participation from Scout Ventures, Samsung Ventures, and RTX Ventures, among others. The Santa Clara-based business was founded in 2022.
• AI legal tech company Harvey raised a $300 million Series D round that valued the 3-year-old company at $3 billion. The round was led by Sequoia and announced on February 12. OpenAI Startup Fund, Kleiner Perkins, Elad Gil, and others also participated in the raise.

January

• Synthetic voice startup ElevenLabs raised a $180 million Series C round that valued the company at more than $3 billion. It was announced on January 30. The round was co-led by Iconiq and Andreessen Horowitz. Sequoia, NEA, Salesforce Ventures, and others also participated in the round.
• Hippocratic AI, which develops large language models for the healthcare industry, announced a $141 million Series B round on January 9. This round valued the company at more than $1.6 billion and was led by Kleiner Perkins. Andreessen Horowitz, Nvidia, and General Catalyst also participated, among others.

This piece was updated on April 23, June 18, August 27, November 26 and January 19, 2026 to include more deals.

This piece has been updated to remove that Abridge is based in Pittsburgh; the company was founded there.